Welcome to Belting Lab Projects We develop innovative solutions strongly motivated by the unmet needs of patients with malignant gliomas. Publications Check our articles Join us! Previous Next Play Pause Contact Mattias Belting, MD/PhD…

https://www.tumor-microenvironment.lu.se/tumor-microenvironment-0- 2023-03-30

https://www.tumor-microenvironment.lu.se/funding- 2023-03-31

MSc. Students We have thesis projects for Masters students in tumor biology. Please, contact Mattias Belting (Mattias [dot] Belting [at] med [dot] lu [dot] se (Mattias[dot]Belting[at]med[dot]lu[dot]se)) directly for more details. Ph.D…

https://www.tumor-microenvironment.lu.se/open-positions- 2023-03-15

Our studies are focused on but not limited to primary brain tumors, which integrates well with the PI’s clinical proficiency as a consultant Neuro-oncologist. Although the overall mortality in cancer is steadily decreasing, major groups of…

https://www.tumor-microenvironment.lu.se/projects- 2021-04-07

Published 2 November 2017 Check out the results of the RASTEN study, a phase III randomized trial in a homogenous population of lung cancer patients, which investigates the role of low molecular weight heparin (LMWH) in the prevention of…

https://www.tumor-microenvironment.lu.se/article/rasten-trial-investigating-survival-effect-lmwh-enoxaparin-lung-cancer-patients- 2023-03-30

Per Bengtson; PhD, postdoc Erika Bourseau-Guilmain; PhD, postdoc Myriam Cerezo-Magaña; PhD Helena Christianson; PhD Vineesh Indira Chandran; PhD, postdoc Paulina Kucharzewska; PhD Jon Lidfeldt; MD student Eva Lindqvist; Biomedical…

https://www.tumor-microenvironment.lu.se/alumni- 2023-03-07

Published 24 January 2019 We explored plasma extracellular vesicle immunoprofiling as a tool for noninvasive diagnosis of glioma. The tumor microenvironment group and collaborators published results showing the utility of extracellular…

https://www.tumor-microenvironment.lu.se/article/using-plasma-non-invasive-method-glioma-diagnosis- 2023-03-28

Published 6 September 2018 We organized the 2018 Lund-Uppsala brain tumor meeting in Arild, bringing together basic and clinical research groups from both universities. Sweden has a strong tradition in brain tumor research that is well…

https://www.tumor-microenvironment.lu.se/article/lund-uppsala-brain-tumor-meeting- 2021-04-27

Published 20 April 2016 Hypoxia modulates global membrane proteome turnover in cancer cells, providing opportunities for tumor specific drug delivery. Hypoxia promotes tumour aggressiveness and resistance of cancers to oncological…

https://www.tumor-microenvironment.lu.se/article/hypoxia-modulates-global-membrane-proteome-turnover-cancer-cells- 2023-03-28

Published 15 August 2016 In this study, we provide new insight into how cancer cells adapt to stress factors present within the tumor microenvironment through increased uptake of lipoproteins. We provide evidence of a novel role of heparan…

https://www.tumor-microenvironment.lu.se/article/cancer-cells-adapt-stress-through-increased-uptake-lipoproteins- 2023-03-30

Published 14 June 2019 See here how lipid loading may be involved in the paracrine crosstalk between cancer cells and stromal compartment of the hypoxic tumor microenvironment. In this paper, Belting Lab  team and collaborators investigate…

https://www.tumor-microenvironment.lu.se/article/revealing-role-lipid-droplets-accumulation-glioma-development- 2023-03-28

Published 15 November 2018 The Swedish Research Council has decided which applications have been granted grants for medicine and health in 2018. In total, Vetenskapsrådet granted more than SEK 1.2 billion for the years 2018–2023,…

https://www.tumor-microenvironment.lu.se/article/belting-group-receives-competitive-grant-90-msek-swedish-research-council- 2023-03-28

Published 10 September 2019 Created with BioRender.com We explored how the proteome of secreted extracellular vesicles (EVs) may reflect hypoxic glioma cells and provided proof-of-concept for targeted proteomic profiling of glioma derived…

https://www.tumor-microenvironment.lu.se/article/novel-strategy-non-invasive-diagnosis-brain-tumor-patients- 2023-03-28

Published 25 February 2022 On February 2022 our group had a new paper released in the journal PNAS, titled “Landscape of Surfaceome and Endocytome in Human Glioma is Divergent and Depends on Cellular Spatial Organization”, which describes…

https://www.tumor-microenvironment.lu.se/article/our-new-study-reveals-proteomics-based-procedure-potential-immunotarget-identification-glioma- 2023-03-30

Published 20 June 2022 On Tuesday, June 16th, Myriam successfully defended her PhD thesis entitled "Adaptation to Microenvironmental Stress in Glioblastoma - Mechanistic Studies and Potential Targets" at Lund University. Held at…

https://www.tumor-microenvironment.lu.se/article/we-celebrate-myriams-successful-phd-thesis-defense- 2023-03-30

Published 2 May 2022 On April 29th, Emelie Gezelius successfully defended her PhD thesis titled “Coagulation and other aspects of the cardiovascular system in small cell lung cancer” at the Lecture Hall of the Radiotherapy building. The…

https://www.tumor-microenvironment.lu.se/article/our-lab-commemorates-emelies-successful-completion-phd-defense- 2023-03-28

Published 1 March 2021 On this new paper released on March 2021, Myriam Cerezo-Magaña and collaborators explore the interplay between hypoxia, lipid scavenging, proteoglycans and lipid storage. The paper, titled "Hypoxic Induction of…

https://www.tumor-microenvironment.lu.se/article/new-paper-published-describes-how-proteoglycan-dependent-endocytosis-feeds-gliomas-lipid-uptake- 2023-03-30

Top 10 selected publications   See all our publications at Pubmed and Google Scholar   Governa V, Talbot H, Gonçalves de Oliveira K, Cerezo-Magaña M, Bång-Rudenstam A, Johansson MC, Månsson AS, Forsberg-Nilsson K, Marko-Varga G, Enríquez…

https://www.tumor-microenvironment.lu.se/publications- 2023-03-15

  Mattias Belting, MD/PhD Principal InvestigatorProfessor of oncologySenior consultant of oncology Mattias [dot] Belting [at] med [dot] lu [dot] se (Mattias[dot]Belting[at]med[dot]lu[dot]se)+46 -46 -17 85 49Research ProfileProjects   Maria…

https://www.tumor-microenvironment.lu.se/team- 2023-03-29

52074 Onkologi 1_19 42 onkologi i sverige nr 1 – 19 ••• neuro-onkologisk utveckling Nytt grepp för effektivare diagnostik och behandling Elakartade hjärntumörer fortsätter att vara mycket svårbehandlade och drabbar såväl vuxna som barn…

https://www.tumor-microenvironment.lu.se/sites/tumor-microenvironment.lu.se/files/neuro_oncology_development_in_arild_0.pdf