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Using plasma as a non-invasive method for glioma diagnosis

Ressonance image of glioblastoma patients. Photo.

We explored plasma extracellular vesicle immunoprofiling as a tool for noninvasive diagnosis of glioma.

The tumor microenvironment group and collaborators published results showing the utility of extracellular vesicles (EVs) as a method to perform non-invasive liquid biopsy for glioma diagnosis.

Of significant clinical relevance, gliomas are relatively inaccessible for invasive biopsy due to risks of complications, which frequently cause delayed treatment onset, considerable psychological distress for the patient, and ultimately worse patient outcome. 

However, profiling EVs extracted from patient's plasma has showed to be a promising technique to provide less stressfull glioma diagnosis.